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Bone Marrow Transplant Clinical Trials

 

 Key Words

Study Title

 

  Status

 AMD3100, Peripheral Blood Stem Cells, Transplantation, RP124 Compassionate Use Protocol for the Use of AMD3100 to Mobilize Peripheral Blood Stem Cells for Collection and Transplantation Open to Entrollment
 Pediatric Leukemia, Myelodysplasia, Umbilical Cord Blood (UCB Transplantation, RP127  Multi-center, Open Label, Randomized Trial Comparing Single versus Double Umbilical Cord Blood (UCB) Transplantation in Pediatric Patients with Leukemia and Myelodysplasia Open to Enrollment
 Marrow Transplantation, HLA-Matched Family Members, Severe Aplastic Anemia, RP128 Cyclophosphamide and Antithymocyte Globulin Conditioning Regimen for Marrow Transplantation from HLA-Matched Family Members for Severe Aplastic Anemia:  Effect of Marrow Cell Dose on Chronic Graft-vs.-Host Disease:  A Multi-Center Trial Open to Enrollment
 Allogeneic Stem Cell Transplantation, Myelofibrosis, RP129 Study of Fludarabine Based Conditioning for Allogeneic Stem Cell Transplantation for Myelofibrosis  Open to Enrollment
 Randomized Trial, Prophylaxis, Hematopoietic StemCell Transplantation, Relapsed ALL, RP130 A Randomized Trial of Sirolimus-Based Graft versus Host Disease Prophylaxis after Hematopoietic Stem Cell Transplantation in Relapsed ALL Open to Enrollment
 Unrelated bone marrow transplant, unrelated stem cell transplant, allogenetic transplant Development of a National Marrow Donor Program Research Database for Unrelated Stem Cell Transplantion Open to Enrollment
 Unrelated bone marrow transplant, unrelated stem cell transplant, allogenetic transplant NMDP Research Sample Depository for Unrelated Stemm Cell Transplantation Research Open to Enrollment
 Stem cell transplantation, bone marrow donation Study of G-CSF-moblized pheriperal sblood stem cells versus marrow collection for transplantation Open to Enrollment
 

Unrelated matched siblings, patients with hematologic malignancies, GVHD, unrelated stem cell transplant

 Study to determine the most promising postgrafting immunosuppression for prevention of acute GVHD after unrelated donor G-CSF mobilized peripheral blood monuclear stem cell transplantation Open to Enrollment
 AML >55, Related sibling donors (MRD) Nonmyeloablative Allogeneic Peripheral Blood Stem Cell Transplantation from HLA Matched Related Donors for Treatment of Older Patients with De Novo or Secondary Acute Myeloid Leukemia in First Complete Remission Open to Enrollment
 Patients with low or falling donor T-cell chimerism s/p NMSCT Pentostatin and donor lymphocyte infusion for low donor t-cell chimerism after hematopoietic cell transplantation using nonmyeloablative conditioning - a mulit -center trial Open to Enrollment
 Patients with hematologic malignancies, Allogeneic Bone marrow transplant from HLA-idential sibling donor, single antigen mismatched related or unrelated donor, marrow/PBSC or cord blood available for marrow donation Rapamyucin for Immunosuppression and B cell Modulation post stem cell transplant for acute lymphoblastic leukemia Open to Enrollment
 Patients with hematologic malignancies Study comparing meiloablative to nonmyeloablative transplant conditioning in patients with myuelodyspastic syndrome or acute myelogenous leukemia Open to Enrollment
 Patients with hematologic malignaicies (related donor), decreased risk of rejection, no BMT within 6-8 months Comparison of nonmyeloablative conditioning with TBI versus Fludarabine/TBI for HLA-matched related hematopoietic cell transplantation Open to Enrollment
 Pulmonary Hypertension, Myelofibrosis, Bone Marrow, Scarring, Flolan Reversible Secondary Myelofibrosis or Clonal Myeloproliferative Disorder, IRB 17806 Open to Enrollment
 HLA matched related hematopoetic stem cell transplantation, increased risk of rejection, BMT within 6 months Study of nonmyeloablative conditioning with TBI or fludarabine/TBI Open to Enrollment
 

 

Retrospective Clinical Database

 International Blood and Marrow Transplant Registry and Autologous Bone Marrow Transplant Registry - Development of outcomes databases Open to Enrollment
 Campath, allogeneic transplants with mis-matched related and unrelated donors, RP93 Campath®  [Alemtuzumab] Dose Escalation, Low-Dose TBI and Fludarabine Followed by HLA Class I Mismatched Donor Stem Cell Transplantation for Patients with Hematologic Malignancies – A Multi-Center Trial Open to Enrollment
 Retrospective Clinical Database, RP126 Assessment of the Correlation between Pre-transplant Comorbidities and Post-Transplant Outcomes Using the Hematopoietic cell Transplantation-Specific Comorbidity Index (HCT-CI):  A Multi-Center Trial Open
 Paroxysmal Nocturnal Hemoglobinuria, Hematopoietic Stem Cell, Prion Protein  

Role of Prion Protein in Human Hematopoietic Stem Cells

 Open to Enrollment
 Resistant lymphoma requiring auto/allo Study of autologous stem cell transplantation followed by non-myeloablative allogeneic stem cell transplantation for patients with relapsed or refractory lymphoma Closed to Enrollment

Department of Internal Medicine
Clinical Trials
30 N 1900 E,
Salt Lake City, Utah 84132
(801) 581-7606
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