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Matthew Samore, MD

Professor
Division of Epidemiology  
Department of Internal Medicine
Matthew.Samore@hsc.utah.edu

 

Professor of Medicine, Adjunct Professor of Biomedical Informatics.  Dr. Samore is the Director of the Salt Lake IDEAS Center and Chief of the Division of Epidemiology at the University of Utah. He attended the University of Wisconsin School of Medicine, completed his residency in Internal Medicine at Washington University in St. Louis, and his Fellowship in Infectious Diseases at Brigham and Women's Hospital and Beth Israel Hospital in Boston.  Dr. Samore was a member of the faculty of Harvard Medical School for 8 years. His research mentors included Drs. Jonathan Freeman, Mark Roberts, Richard Platt, Donald Goldmann, and AW Karchmer.  Dr. Samore’s expertise encompasses epidemiologic methods, computer-based surveillance, and decision support systems.  Dr. Samore has spearheaded program building efforts in health services research at the VA Salt Lake City Health Care System and University of Utah.  He has broad-based experience in leading inter-disciplinary research programs.  He is a member of the HSR&D Scientific Review and Evaluation Board (SREB), Subcommittee for Career Development and of the Agency for Health Care Research and Quality (AHRQ) Health Care Research Training (HCRT) Study Section.
 

Research Interests

Dr. Samore is focused on developing infrastructure for research through data integration. Major goals are to improve the health of veterans through foundational and applied informatics research to advance the effective use of unstructured text and other types of clinical data in the electronic health record. His other goals are to conduct research and lead programs that reduce the burden of healthcare-related infections and other types of adverse events and to plan to increase the interchange between University investigators and the citizens of Utah and surrounding states.

Dr. Samore is leading or participating in several randomized or quasi-experimental intervention trials that address antimicrobial resistance and other studies that apply computer-based approaches to surveillance and/or antibiotic prescribing.  These include the CMS-funded RADAR (Rural Antibiotic Decision-Support And Resistance) project, the CDC-funded IMPART (Inter-Mountain Project on Antimicrobial Resistance and Therapy), an FDA sponsored study of adverse event surveillance, and the AHRQ-funded INFORM (Intelligent Network for Orders, Registry, and Management) project.
 

Select Publications

Ampofo K, Gesteland PH, Bender J, Mills M, Daly J, Samore M, Byington C, Pavia AT, Srivastava R. Epidemiology, complications, and cost of hospitalization in children with laboratory-confirmed influenza infection. Pediatrics. 2006 Dec;118(6):2409-17.

Rubin MA, Bateman K, Donnelly S, Stoddard GJ, Stevenson K, Gardner RM, Samore MH. Use of a personal digital assistant for managing antibiotic prescribing for outpatient respiratory tract infections in rural communities. J Am Med Inform Assoc. 2006 Nov-Dec;13(6):627-34. Epub 2006 Aug 23.

Madaras-Kelly KJ, Hannah EL, Bateman K, Samore MH. Experience with a clinical decision support system in community pharmacies to recommend narrow-spectrum antimicrobials, nonantimicrobial prescriptions, and OTC products to decrease broad-spectrum antimicrobial use.
J Manag Care Pharm. 2006 Jun;12(5):390-7.

Erbay A, Ergonul O, Stoddard GJ, Samore MH. Recurrent catheter-related bloodstream infections: Risk factors and outcome. Int J Infect Dis. 2006 Sep;10(5):396-400. Epub 2006 May 15.

Samore MH, Venkataraman L, DeGirolami PC, Merrigan MM, Johnson S, Gerding DN, Carmeli Y, Harbarth S. Genotypic and phenotypic analysis of Clostridium difficile correlated with previous antibiotic exposure.Microb Drug Resist. 2006 Spring;12(1):23-8. 

Gundlapalli AV, Rubin MA, Samore MH, Lopansri B, Lahey T, McGuire HL, Winthrop KL, Dunn JJ, Willick SE, Vosters RL, Waeckerle JE, Carroll KC, Gwaltney JM Jr, Hayden FG, Elstad MR, Sande MA. Influenza, Winter Olympiad, 2002. Emerg Infect Dis. 2006 Jan;12(1):144-6. 

Nebeker JR, Virmani R, Bennett CL, Hoffman JM, Samore MH, Alvarez J, Davidson CJ, McKoy JM, Raisch DW, Whisenant BK, Yarnold PR, Belknap SM, West DP, Gage JE, Morse RE, Gligoric G, Davidson L, Feldman MD. Hypersensitivity cases associated with drug-eluting coronary stents: a review of available cases from the Research on Adverse Drug Events and Reports (RADAR) project.
J Am Coll Cardiol. 2006 Jan 3;47(1):175-81. Epub 2005 Dec 1. 

Samore MH, Lipsitch M, Alder SC, Haddadin B, Stoddard G, Williamson J, Sebastian K, Carroll K, Ergonul O, Carmeli Y, Sande MA. Mechanisms by which antibiotics promote dissemination of resistant pneumococci in human populations. Am J Epidemiol. 2006 Jan 15;163(2):160-70. Epub 2005 Nov 30. 

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